|
BAXTER ANNOUNCES THE LAUNCH OF FIRST-OF-ITS-KIND CHRONIC KIDNEY DISEASE
RESEARCH PROGRAM TO DEVELOP A NEW MODEL OF RENAL DISEASE CARE
Partnership with Leading Academic Institutions and
Nephrologists in North America Aims to Set New Standard of Care for At-Risk
Kidney Disease Patients
SAN DIEGO, Calif., November 14, 2003 - Baxter Healthcare Corporation
today announced the launch of the Chronic Kidney Disease (CKD) research
program at the 2003 American Society of Nephrology (ASN) annual meeting
in San Diego. In partnership with leading North American academic institutions
and nephrology practices, including Harvard University (Cambridge, Mass.),
Hospital of St. Raphael (New Haven, Conn.), Royal Victoria Hospital/McGill
University Centre (Montreal, Quebec), Mid-Atlantic Nephrology Associates
(Baltimore, Md.), Nephrology Associates (Birmingham, Ala.), Humber River
Regional Hospital (Toronto, Canada) and Queen Elizabeth II Health Sciences
Center (Halifax, Nova Scotia), Baxter believes the first-of-its-kind research
collected from the program will help create a new model of renal care
designed to encourage earlier kidney disease detection and treatment and,
ultimately, greater survival for patients.
The complexity of
chronic kidney disease (CKD), including comorbidities such as diabetes
and hypertension, has made it difficult to manage CKD patients. This program
aims, for the first time, to prescribe a meaningful and integrated model
of CKD care to provide more timely initiation of medical intervention
and treatment. Specifically, the program will examine the long-term clinical
needs of chronic kidney disease (CKD) patients who have not yet progressed
to dialysis treatment. Established research suggests that CKD patients
who visit a nephrologist during the less-advanced stage of the disease
are more apt to: comply with treatment; practice better self-care; better
manage comorbidities (including diabetes and high-blood pressure); and
ultimately extend their survival while on dialysis therapy.
"The CKD program
will be the first concerted and long-term effort to study chronic kidney
disease patients as their disease progresses. By documenting the current
delivery of care we hope to influence both diagnosis and treatment practices
to potentially delay the need for dialysis and, most importantly, offer
the opportunity for greater survival," said Salim Mujais, M.D., vice
president of Global Medical Affairs for Baxter's Renal business.
A significant advantage
of the program is the use of paper-less, computerized technology for gathering
patient information to evaluate, categorize, track and report patient
information in real-time. This will allow program participants and other
healthcare providers, for the first time ever in CKD care, to provide
immediate feedback to a multidisciplinary team and to act on information
to provide more responsive and efficient patient care.
According to the National
Kidney Foundation of America and the Kidney Foundation of Canada, more
than 500,000 Americans and Canadians are being treated for kidney disease.
Additionally, the incidence of end-stage renal disease (ESRD), requiring
some form of renal dialysis or transplantation, is growing globally at
a rate of five-to-six percent annually. Diabetes is the leading cause
of kidney failure in both countries. In the U.S., 17 million people have
diabetes, while in Canada two million people have diabetes and another
2.5 million are at risk of developing the disease.
Traditionally, kidney
disease patients are seen by a nephrologist when the disease has reached
an advanced stage ultimately requiring dialysis. Late treatment referrals
offer less opportunity to choose the most optimal treatment for a patient.
They also can result in earlier patient deaths.
"Given the growing
incidence of diabetes, high-blood pressure and obesity in North America,
kidney disease and, ultimately, kidney failure present a great public
health challenge," said Fred Finkelstein, M.D., clinical professor
of medicine at Yale University and Chief of Nephrology at the Hospital
of St.Raphael, New Haven, Conn., and CKD program participant. "Better
understanding the needs of kidney disease patients before the disease
progresses and dialysis is required, can potentially improve treatment
outcomes and lead to greater survival."
"The CKD program
is the most unique approach to understanding the needs of CKD patients
that I have seen during my 18 years in nephrology. The use of a computerized
system where patient information can be quickly gathered and analyzed
by multiple members of the CKD care team -- beyond the nephrologist --
to make immediate treatment decisions is a first in CKD care. The program
can lead to ground-breaking changes in the way these patients are currently
diagnosed and managed, and that can change lives dramatically for the
better," said David Mendelssohn, M.D., associate professor of medicine
at the University of Toronto and Head of the Division of Nephrology at
Humber River Regional Hospital, Toronto, Canada, also a CKD program participant.
How the Chronic
Kidney Disease (CKD) Program Works: Utilizing Same-Time Technology for
Better Patient Care
Educational and clinical
research results from the program are expected to be released within the
next two years. The CKD program's objectives are unique among efforts
to understand this patient group. It is designed to promote advanced CKD
education to patients, better engaging and empowering them to take an
active role in their own care. The program will examine these patients
over the long-term course of their disease. Additionally, the program
will prescribe a multi-disciplinary approach to CKD care, with tailored
care pathways to address renal disease progression, anemia, hypertension,
nutrition and preventive care, among other elements -- all contributing
factors to the progression or regression of CKD.
A multi-disciplinary
team will work together to quickly recognize, capture and share patient
information gathered by the use of computerized, same-time technology
to initiate more timely decision-making and patient care. For example,
information on a patient's diabetes status and nutrition are entered into
the CKD program software system and shared with an integrated team of
health-care professionals, including a nephrologist, nutritionist, nurse,
and a social worker, so that all members of a patient's CKD care team
have access to the information and the opportunity to add analysis and
recommendations based on their specialties. Program participants believe
this unique level of organization and quick reaction can potentially improve
patient care and survival.
The program will include
several special research projects to better understand current issues
of particular importance in nephrology including: CKD treatment practices
and modality selection, examination of common comorbidities (diabetes,
high-blood pressure and cardiovascular concerns) and their impact on CKD
care, the progression of CKD, and the potential health economics benefit
in earlier diagnosis and treatment of CKD. The data collection tool used
in the CKD program will be incorporated into Baxter's RenalSoft software
suite. Additional analysis of the data can be achieved with the software
program.
About ESRD (End-Stage
Renal Disease) and Dialysis Treatment Options
ESRD is an advanced
stage of chronic kidney disease that requires some form of renal replacement
therapy. The incidence and prevalence of ESRD have doubled in the past
10 years and are expected to continue to grow. Worldwide, approximately
1.5 million patients are being treated for ESRD. More information on ESRD
and its treatments can be found on www.kidneydirections.com.
Two forms of dialysis are most commonly available to ESRD patients: peritoneal
dialysis (PD) and hemodialysis (HD).
In PD, extra fluids
and waste are removed from the blood inside the body, using the body's
own peritoneal membrane, or abdominal lining, as a natural filter. In
this form of dialysis, blood never leaves the body. Dialysis fluid enters
the peritoneal cavity through a flexible catheter surgically inserted
in the abdomen. Extra fluid and waste travel across the peritoneal membrane
into the dialysis fluid, which is then drained from the abdomen through
the catheter after a pre-determined dwell period.
During HD, blood is
removed from the body through needles inserted into a blood vessel. The
blood is then pumped through a machine containing an artificial kidney
filter called a dialyzer that cleanses the blood, which is returned back
to the body. Most HD patients receive treatment at a special dialysis
center and typically require four-hour dialysis sessions three times a
week. A team of trained health-care professionals supervise and deliver
therapy during the dialysis sessions.
About Baxter
Baxter's Renal business
provides a complete and complementary portfolio of dialysis-related products
used in the treatment of patients with kidney disease, including dialysis
systems and solutions, pharmaceuticals and biotechnology products.
Baxter Healthcare
Corporation is the principal domestic operating subsidiary of Baxter International
Inc. (NYSE: BAX). Baxter International Inc., through its subsidiaries,
assists health care professionals and their patients with treatment of
complex medical conditions, including cancer, hemophilia, immune disorders,
kidney disease and trauma. The company applies its expertise in medical
devices, pharmaceuticals and biotechnology to make a meaningful difference
in patients' lives.
This news release contains forward-looking statements that involve
risks and uncertainties, including technological advances in the medical
field, product demand and market acceptance, the impact of competitive
products and pricing, actions of regular bodies and other risks detailed
in the company's filings with the Securities and Exchange Commission.
These forward-looking statements are based on estimates and assumptions
made by management of the Company and are believed to be reasonable, though
are inherently uncertain and difficult to predict. Actual results or experiences
related to the CKD Program could differ materially from the forward-looking
statements.
FOR
ADDITIONAL INFORMATION:
|

|
- Media
Contacts:
-
Ilke Arici,
847-948-3272
Rick Moser, 847-948-3784
|
 |
- Investor Contacts:
-
Neville Jeharajah, 847-948-2875
Mary Kay Ladone, 847-948-3371
|
2003 American Society
of Nephrology Annual Meeting - Baxter Booth # 501
|