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BAXTER
ANNOUNCES LAUNCH OF ARALAST FOR PATIENTS WITH HEREDITARY
EMPHYSEMA IN NEED OF NEW THERAPY
DEERFIELD, Ill, May
30, 2003 -- Baxter announced today the launch of Aralast,
a new alpha-1 antitrypsin therapeutic, also known as Alpha 1 proteinase
inhibitor (A1PI) for the treatment of hereditary emphysema. Aralast
will be available this month exclusively through specialty pharmacy providers,
including Accredo Health Inc., Caremark Inc. and Coram Healthcare.
"A1PI deficiency
results in a form of hereditary emphysema and people living with this
condition require appropriate treatment to protect against long-term lung
damage," said James M. Stock, M.D., professor of Medicine, University
of Texas Health Center. "Aralast provides a new important treatment
option for patients."
Baxter was named the
exclusive distributor of Aralast by Alpha Therapeutic Corporation in December
2002. As was previously announced, both companies continue to work toward
completion of a definitive agreement in which Baxter will acquire all
rights to Aralast and all of Alpha Therapeutic Corporation's plasma collection
operations. Until the completion of that transaction, Alpha Therapeutic
Corporation will continue to process limited supplies of the therapy.
Following a complete transition of the entire processing operation to
Baxter, plans are in place to gradually increase supplies of Aralast from
now through 2005.
"We are committed
to making the current supplies of Aralast available because we recognize
the lack of options that have been available to this patient population,"
said Larry Guiheen, president of Biopharmaceuticals at Baxter. "Aralast
also leverages Baxter's history of success in the processing of therapeutic
proteins to help address the needs of this marketplace."
Baxter selected three
specialty pharmacy providers to provide Aralast, along with a comprehensive
offering of nationwide homecare services, to support patients with hereditary
emphysema. These services include comprehensive care from a team of experienced
pharmacists and nurses, physician-coordinated treatment plans, information
on reimbursement programs, advocacy programs, therapy education and nursing
support.
According to the Alpha-1
Foundation, A1PI deficiency affects an estimated 100,000 people in the
United States and results in a form of hereditary emphysema. People with
this deficiency have reduced serum levels of A1PI, an important blood
protein processed in the liver. This protein helps protect lung tissue
from damage caused by enzymes that are released by white blood cells.
Without sufficient quantities of A1PI, patients develop lung damage. If
untreated, A1PI can result in emphysema and premature death.
A1PI deficiency should
be treated by a weekly infusion of a plasma-derived alpha-1 proteinase
inhibitor like Aralast. This therapeutic approach is not a cure nor will
it reverse lung damage that has already occurred. However, it does protect
the lungs from further damage, making early diagnosis and treatment desirable.
Patients and physicians
who want information about obtaining Aralast
should contact Baxter at 1-800-423-2090.
Alpha Therapeutic
Corporation is a leading developer of plasma-derived biopharmaceutical
therapies. Alpha's therapy portfolio includes coagulation factors, immune
globulin and albumin, which are distributed domestically to hospitals,
pharmacies, homecare companies and physicians. Internationally, Alpha's
therapies are marketed through a network of subsidiaries, affiliates and
local offices in Asia, Europe and Latin America.
Baxter Healthcare
Corporation is the principal U.S. operating subsidiary of Baxter International
Inc. (NYSE: BAX). Baxter assists health-care professionals and their patients
with treatment of complex medical conditions, including cancer, hemophilia,
immune disorders, kidney disease and trauma. The company applies its expertise
in medical devices, pharmaceuticals and biotechnology to make a meaningful
difference in patients' lives. For more information about Baxter, please
visit www.baxter.com.
This news release
contains forward-looking statements that involve risks and uncertainties,
including actions of regulatory bodies, market demand, the impact of competitive
products and pricing, technological advances in the medical field, completion
of definitive agreements and other risks detailed in the company's filings
with the Securities and Exchange Commission. These forward-looking statements
are based on estimates and assumptions made by management of the company
and are believed to be reasonable, though are inherently uncertain and
difficult to predict. Actual results or experience could differ materially
from the forward-looking statements.
FOR
ADDITIONAL INFORMATION:
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Media Contacts:
Deborah Spak, 847-948-2349
Cindy Resman, 847-948-2815
Investor Contacts:
- Neville Jeharajah,
Baxter, 847-948-2875
Mary Kay Ladone, Baxter, 847-948-3371
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