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BAXTER
AND CERUS ANNOUNCE THE FIRST CUSTOMERS FOR THE INTERCEPT BLOOD SYSTEM
Blood Centres
in Portugal and Italy Set a New Trend to Enhance the Safety of Blood Transfusions
in Europe
BRUSSELS, BELGIUM
and CONCORD, CALIF., January 20, 2003--Subsidiaries of Baxter International
Inc. and Cerus Corporation announced today that The Centro Regional de
Sangue in Lisbon, Portugal and the Transfusion Centre in Palermo, Italy
are the first two blood centres in Europe to implement the new blood safety
technology, the INTERCEPT Blood System for platelets. The INTERCEPT Blood
System is designed to protect patients by reducing the risk of transfusion-transmitted
diseases by inactivating certain known and potential emerging pathogens
in blood components.
"We decided to
implement the INTERCEPT Blood System for platelets because it is important
to us that our patients receive the best available care," said Dr.
Gracinda de Sousa director of the Lisbon Blood Centre. "Until recently,
detection of pathogens through screening tests had been the standard safety
procedure in western European countries. However, screening tests have
certain limitations."
Dr. Rosalia Agliastro director of the Palermo Transfusion Centre in Italy
said, "Even the best screening technologies can leave a window period
for infection and they do not detect emerging viruses, which can compromise
the safety of our blood supplies."
Also reinforcing the
use of new blood safety technology is the EU Blood directive, which the
European Parliament and Council approved in December 2002 to introduce
wide uniformity of safety standards for human blood and blood components
and to increase the quality and safety of blood throughout Europe. In
order to reduce the risk of contamination in donated blood, the directive
has outlined the necessity of using the latest technologies that take
advantage of scientific advances in the detection, inactivation and elimination
of pathogens that can be transmitted via transfusion.
The INTERCEPT Blood
System has been jointly developed by Baxter and Cerus. With this technology,
the two companies introduce a new, more comprehensive strategy for the
protection of the blood supply by targeting certain pathogens associated
with transfusion-transmitted diseases. The INTERCEPT Blood System for
platelets uses a light-activated, nucleic acid-targeting compound that
inactivates pathogens containing DNA and RNA, such as HIV and Hepatitis
B and C, and renders them harmless by preventing them from replicating.
Patients in Europe undergoing chemotherapy, heart bypass surgery and other
procedures that require platelet transfusions are expected to benefit
from this technology.
Earlier this month,
the European Union approved the INTERCEPT Blood System for use with apheresis
platelets, while application with buffy coat platelets was approved in
the European Union in October 2002. The INTERCEPT Blood System is the
only pathogen inactivation system that is approved and available for use
in Europe with platelets. INTERCEPT Platelets are currently being validated
in several countries, including Belgium, Germany, Denmark, France, Norway,
Sweden and the United Kingdom. Clinical trials are underway for use with
plasma and red blood cells for transfusion, making the INTERCEPT Blood
System the only pathogen inactivation technology currently being developed
for use with all primary blood components.
Baxter International
Inc. is a global health care company that, through its subsidiaries, provides
critical therapies for people with life-threatening conditions. Baxter's
bioscience, medication delivery and renal products and services are used
to treat patients with some of the most challenging medical conditions
including cancer, hemophilia, immune deficiencies, infectious diseases,
kidney disease and trauma.
Cerus Corporation
is developing medical systems and therapeutics based on its proprietary
Helinx technology for controlling biological replication. Cerus' most
advanced programs are focused on systems to enhance the safety of blood
products used for transfusion. The INTERCEPT Blood System, based on the
Cerus Helinx technology, is being developed to inactivate viruses, bacteria,
parasites and white blood cells. The Concord, California-based company
also is pursuing therapeutic applications of Helinx technology to treat
and prevent serious diseases.
Cerus and Helinx are
U.S. registered trademarks of Cerus Corporation.
Baxter and INTERCEPT are trademarks of Baxter International Inc.
Statements in this
news release regarding regulatory filings, product development and commercial
potential are forward-looking statements that involve risks and uncertainties.
Actual results could differ materially from the above forward-looking
statements as a result of certain factors, including the risks and uncertainty
of the timing and results of clinical trials and other development activities,
actions by regulatory authorities at any stage of the development and
commercialization process, additional financing activities, manufacturing,
market acceptance of any products, competitive conditions and other factors
discussed in the companies' most recent filings with the Securities and
Exchange Commission.
FOR ADDITIONAL
INFORMATION:
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- Cerus:
Media
and Investor Relations:
Sylvia Wheeler, (925) 288-6061
Baxter:
- Media Contacts:
- Patty O'Hayer,
32 2 650 1924, Europe
Tanya Tyska, (847) 270-4918, North America
- Jed Weiner,
(847) 270-3928, North America
- Investor Contacts:
- Neville Jeharajah,
Baxter, (847) 948-2875
Mary Kay Ladone, Baxter, (847) 948-3371
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