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BAXTER TO ACQUIRE ALPHA-1 ANTITRYPSIN AND OTHER ASSETS FROM ALPHA THERAPEUTIC
CORPORATION
DEERFIELD, Ill., December
20, 2002 -- Baxter Healthcare Corporation today announced that it has
entered into a definitive agreement to acquire certain assets from Alpha
Therapeutic Corporation. Alpha Therapeutic Corporation is owned by Mitsubishi
Pharma Corporation. Under the agreement, Baxter will obtain Alpha Therapeutic
Corporation's Alpha-1 Antitrypsin (A1P1) product, which is undergoing
FDA review for the treatment of hereditary emphysema, and all of Alpha
Therapeutic Corporation's plasma collection operations, which include
42 FDA-licensed plasma collection centers in the United States, and a
central testing laboratory.
"Alpha-1 Antitrypsin will expand Baxter's BioScience product portfolio
of biopharmaceuticals, as well as broaden our therapeutic focus in the
pulmonology arena," said Thomas Glanzmann, senior vice president
and president, Baxter BioScience. "In addition, this transaction
further enhances the economics of our plasma business by increasing the
number of fractions Baxter obtains from a liter of plasma."
Alpha Therapeutic Corporation will also lease to Baxter those facilities
necessary for the production of A1P1, pending FDA licensure and the transfer
of these manufacturing activities to Baxter facilities.
Under the agreement, the financial terms of the transaction will not be
disclosed. Closing of the transaction is subject to approval by regulatory
authorities. This transaction is expected to close in the first half of
2003. In accordance with Generally Accepted Accounting Principles, a portion
of the purchase price will be allocated to in-process research and development.
Excluding this charge, Baxter expects this acquisition to be non-dilutive
in 2003.
Hereditary emphysema is a disease characterized by abnormally low levels
of the protease inhibitor Alpha-1 Antitrypsin (AAT). An estimated 200,000
people in the United States and Europe have the deficiency, and about
half of these patients are symptomatic. If left untreated, it can lead
to liver disease, emphysema and premature death. It is often misdiagnosed
as asthma or Chronic Obstructive Pulmonary Disease (COPD) and less than
10% of patients are properly diagnosed. The World Health Organization
(WHO) recommends that all individuals with COPD and asthma be tested for
the deficiency with a simple blood test. Currently there is only one plasma-derived
AAT licensed in the United States, which has been in very limited supply.
Many of the diagnosed patients have therefore not had access to AAT treatment.
Baxter BioScience develops and produces biopharmaceuticals from plasma
and through recombinant methods to treat hemophilia, immune deficiencies
and other blood-related disorders, as well as vaccines and biosurgery
products.
Baxter Healthcare Corporation is the principal domestic operating subsidiary
of Baxter International Inc., (NYSE: BAX), a global health care company
that, through its subsidiaries, provides critical therapies for people
with life-threatening conditions. Baxter's bioscience, medication delivery
and renal products and services are used to treat patients with some of
the most challenging medical conditions, including cancer, hemophilia,
immune deficiencies, infectious diseases, kidney disease and trauma.
This news release
contains forward-looking statements that involve risks and uncertainties,
including economic conditions, actions of regulatory bodies, market demand,
the impact of competitive products and pricing, technological advances
in the medical field, foreign exchange and other risks detailed in the
company's filings with the Securities and Exchange Commission. These forward-looking
statements are based on estimates and assumptions made by management of
the company and are believed to be reasonable, though are inherently uncertain
and difficult to predict. Actual results or experience could differ materially
from the forward-looking statements.
FOR ADDITIONAL
INFORMATION:
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- Media Contacts:
- Deborah Spak,
847-948-2349
Tali Kaplan, 805-372-3540
- Investor Contacts:
- Neville Jeharajah,
Baxter, 847-948-2875
Mary Kay Ladone, Baxter, 847-948-3371
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