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BAXTER
AND INTERNATIONAL SOCIETY OF NEPHROLOGY ANNOUNCE FIRST ROUND OF RENAL
DISCOVERIES GRANT PROGRAM WINNERS
DEERFIELD, Ill., July
31, 2002 -- Baxter Healthcare Corporation in collaboration with the International
Society of Nephrology (ISN) today announced the first round of Renal
Discoveries grant program recipients representing seven countries
across the globe. Renal Discoveries is an extramural grant program
designed to promote scientific advancement in the field of kidney disease
and its treatment.
"I congratulate the 10 grant winners on their outstanding science,
which will contribute significantly to the advancement and knowledge of
kidney disease and its clinical applicability," said Lee W. Henderson,
M.D., F.A.C.P, the Extramural Grant Program founder. "Our hope and
our goal is that the patient becomes the ultimate winner, as he or she
may benefit from new therapies developed as a result of this grant program."
In April 2002, 96 applicants from 21 countries submitted basic or applied
research proposals on the topic of Inflammation and Kidney Disease.
An independent medical advisory board -- whose membership rotates to ensure
breadth of scientific judgment -- evaluated all applications, judging
them strictly on scientific merit. The board, comprised of members from
the ISN, selected 10 outstanding proposals and awarded up to $50,000 USD
per year for the basic clinical research grants and up to $75,000 USD
per year for the three-year applied research grants. Those granted an
applied clinical research award are eligible to apply for increased funding
up to $300,000 USD in years two and three. Grant winners include:
- Laurent Baud,
M.D., Ph.D., INSERM, Paris, France. "Proteases Involved in
the Activation of Latent Transforming Growth Factor-b (TGF-b) Play a
Role in the Development of Renal Inflammation."
- Giacomo Garibotto,
M.D., University of Genoa, Genoa, Italy. "Effects of Low-grade
Chronic Inflammation on Muscle Protein Turnover in Patients with End-stage
Renal Disease."
- Enyu Imai,
M.D., Ph.D., Osaka University Graduate School of Medicine, Osaka, Japan.
"Proteinuria Induced Inflammatory Reaction in Proximal Tubule."
- Hui Yao Lan,
M.D., Ph.D., Baylor College of Medicine, Houston, Texas. "Role
of Smad Signaling in the Pathogenesis of Hypertensive Nephropathy and
A Novel Therapeutic Potential Using Ultrasound-Microbubble Gene Transfer
of Inducible Smad7."
- Christopher
Y. Lu, MD, Univ. Texas Southwestern Medical Center at Dallas, Dallas,
Texas. "RAE 1, NKG2D, and Innate Leukocytes in Ischemic Acute
Renal Failure."
- Robert H. Mak,
M.D., Ph.D., Oregon Health & Science University, Portland, Oregon.
"Cytokine Signaling and Cachexia in Uremia."
- Andreas Pierratos,
M.D., Humber River Regional Hospital, Toronto, Ontario, Canada.
"Impact of Nocturnal Hemodialysis on the Malnutrition -- Inflammation
-- Atherosclerosis Axis."
- Gregory H.
Tesch, BAppp, Sc, MSc, Ph.D., Monash Medical Centre, Clayton, Victoria,
Australia. "Stress Activated Protein Kinase Signaling: a Key
Pathway for Both Inflammation and Fibrosis in Peritoneal Membrane Dysfunction?"
- David C. Wheeler,
MB, ChB, M.D., Royal Free and University College Medical School, London,
England, United Kingdom. "Molecular Mechanisms and Consequences
of LDL Receptor Dysregulaion by Inflammatory Cytokines."
- Veronique Witko-Sarsat,
Ph.D., INSERM, Paris, France. "Role of Myeloperoxidase and
its Derivatives, the Advanced Oxidation Protein Products (AOPP), in
Chronic Renal Failure."
"The ISN strongly
encourages scientists from across the globe to apply for a grant from
the Renal Discoveries program," said Australia's Professor
Robert C. Atkins, ISN's president. "By applying for a grant, a scientist
is helping to expand knowledge about kidney disease and its treatment
-- a contribution that enriches lives and learning."
Renal Discoveries continues Baxter's support of the study of kidney
disease, including pathophysiology and treatment options, by building
on a previous grant program that distributed more than $25 million to
221 grant winners in 20 countries. It provides needed resources to enable
scientific researchers to pursue broad, long-term basic and applied studies.
Such studies are critical to enhancing the collective knowledge base on
kidney disease and treatment.
Requests for proposals for the program's Round 2 topic, Cardiovascular
Morbidity and Mortality in Kidney Disease, have been distributed worldwide.
Round 2 applications are due by October 11, 2002. More information on
Renal Discoveries, including instructions for preparing a grant
application, can be found at www.baxter.com/egp
and www.isn-online.org.
Renal Discoveries is modeled after grant programs managed by the
United States National Institutes of Health, with topics announced twice
each year and detailed writing instructions to guide applicants through
the process. An independent medical advisory board evaluates applications
based on scientific merit.
The International Society of Nephrology is a truly global organization.
Its membership consists of individual kidney specialists in practically
every country. It has more than 8,000 members worldwide. The Society's
goal is the worldwide advancement of education, science and patient care
in kidney disease.
Baxter is a leading provider of renal products and services worldwide.
In 1956, the company introduced the first disposable coil dialyzer, a
development that greatly enhanced the use and application of hemodialysis.
Nearly 20 years later, Baxter was the first company to introduce continuous
ambulatory peritoneal dialysis products.
Baxter Healthcare Corporation is the principal domestic operating subsidiary
of Baxter International Inc. (NYSE: BAX), a global health care company
that, through its subsidiaries, provides critical therapies for people
with life-threatening conditions. Baxter's bioscience, medication delivery
and renal products and services are used to treat patients with some of
the most challenging medical conditions, including cancer, hemophilia,
immune deficiencies, infectious diseases, kidney disease and trauma.
(Renal Discoveries
is a trademark of Baxter International Inc.)
FOR ADDITIONAL
INFORMATION:
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- Media Contact:
- Lisa Scheff,
847-948-4107
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