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BAXTER RECEIVES
EUROPEAN LICENSURE FOR CEPROTIN,
A TREATMENT FOR PROTEIN C DEFICIENCY
Brussels, Belgium,
July 18, 2001 - Baxter International Inc. announced today that the European
Medicines Evaluation Agency (EMEA) has granted licensure for Ceprotin,
protein C concentrate, for use as a replacement therapy for people suffering
from life-threatening blood clotting complications related to severe congenital
protein C deficiency. Baxter is the first company to receive a license
using the European centralized procedure, a process by which the European
Commission grants authorization which is valid in all member states of
the European Union.
"Continuing our legacy of 'firsts,' we are proud to be the first
company to receive a broad European license for this disease," said
Thomas Glanzmann, senior vice president and president, Baxter BioScience.
"It underscores our commitment to providing critical therapies for
people with unmet medical needs."
Protein C is a component in human plasma which regulates the coagulation
system and prevents abnormal clot formation (thrombosis). Currently, there
is no ideal alternative to specific protein C replacement therapy. Protein
C may be replaced with fresh frozen plasma, but this involves infusing
patients with very large volumes of plasma, which can result in fluid
overload, causing pulmonary edema and hypertension. Other treatment approaches,
such as oral anticoagulation, are associated with a risk of bleeding as
well as inadequate control of the serious and widespread thrombotic disorder.
The incidence of severe hereditary protein C deficiency is approximately
1 in every 200,000 births, and often goes undiagnosed. If left untreated,
the thrombotic lesions which develop can result in blindness, severe brain
damage, multi-organ failure and death. Baxter intends to initiate clinical
trials in acquired Protein C deficiency in the near future.
Baxter is a global medical products and services company that, through
its subsidiaries, provides critical therapies for people with life-threatening
conditions. Baxter's products and services in bioscience (biopharmaceuticals,
vaccines, biosurgery and transfusion therapies), medication delivery and
renal therapy are used by health-care providers and their patients in
more than 100 countries.
This news release contains forward-looking statements that involve
risks and uncertainties, including those related to timing or results
of pending or future clinical trials, actions by regulatory and governmental
bodies, technological advances in the medical field, product demand and
market acceptance and other risks detailed in the company's filings with
Securities and Exchange Commission. These forward -looking statements
are based on estimates and assumptions made by management of the company
and are believed to be reasonable, though are inherently uncertain and
difficult to predict. Actual results or experience could differ materially
from the forward-looking statements.
(Baxter and Ceprotin are trademarks
of Baxter International Inc. and its affiliates)
FOR ADDITIONAL
INFORMATION:
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- Media Contacts:
- Deborah
Spak, (847) 948-2349
Tali Kaplan, (818)
550-4680
Hans Vanavermaete, 32-2-650-1703
- Investor Contacts:
- Neville
Jeharajah, (847) 948-2875
Mary Kay Ladone, (847) 948-3371
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