|
BAXTER
TO EXPAND RECOMBINANT PROTEIN
MANUFACTURING FACILITY
DEERFIELD, Ill., May 10, 2001 - Baxter Healthcare Corporation announced
today that it is moving forward with an investment to build a fourth manufacturing
suite (Suite D) at its Thousand Oaks, California BioScience facility.
The facility is the site of manufacture for Baxter's recombinant Factor
VIII therapy, Recombinate Antihemophilic Factor (rAHF). Factor VIII is
the protein in human blood that is critical for proper blood coagulation
and is deficient in people with hemophilia A.
"We are pleased to be able to further expand our manufacturing capacity
for recombinant Factor VIII," said Thomas Glanzmann, senior vice
president and president of Baxter's BioScience business. "When approved,
this additional suite will enable us to better meet the needs of patients
who rely on this very important therapy."
Since the construction of the first manufacturing suite at the facility
in 1994, Baxter has committed to increasing capacity at this facility.
This commitment is based on the continuing growth in demand for recombinant
Factor VIII, which is driven by numerous factors, including increased
use to prevent bleeding rather than treating patients when bleeds occur.
The fourth suite represents an additional investment in the facility of
over $50 million and will increase manufacturing capacity at the Thousand
Oaks facility by approximately 30 percent. Baxter expects to begin construction
later this year and is targeting late 2004 for regulatory approval of
Suite D.
The company first received regulatory approval for Suite A in 1998. Last
year, Suite B received United States regulatory approval and Suites B
and C received European regulatory approval. The company is targeting
United States regulatory approval of Suite C later this year.
In addition to the Thousand Oaks facility, Baxter also has a multi-purpose
recombinant protein production facility located in Neuchatel, Switzerland.
The Neuchatel facility features two state-of-the-art production suites,
and currently manufactures product used in the continuing clinical trials
of Baxter's next-generation recombinant Factor VIII therapy. Earlier this
year, the company announced plans to build two additional production suites
at Neuchatel, targeting an annual capacity in excess of one billion units
of Factor VIII from this facility.
Hemophilia A is a rare, hereditary, gender-linked disorder caused by the
absence or severe deficiency of Factor VIII. Currently there are more
than 300,000 persons with hemophilia worldwide.
People with hemophilia A infuse themselves with therapeutic clotting factor,
on average, three times per month, unless they are on a preventive regimen,
in which case they could infuse multiple times per week. Barring other
complications or disorders, clinicians expect a near normal life expectancy
for hemophilic infants born today, when patients receive proper treatment.
Baxter Healthcare Corporation is the principal U.S. operating subsidiary
of Baxter International Inc. (NYSE:BAX). Baxter is a global medical products
and services company that, through its subsidiaries, provides critical
therapies for people with life-threatening conditions. Baxter's products
and services in bioscience (biopharmaceuticals, vaccines, biosurgery and
transfusion therapies), medication delivery and renal therapy are used
by health-care providers and their patients in more than 100 countries.
Baxter and Recombinate are trademarks of Baxter International Inc. Baxter
is registered in the U.S. Patent and Trademark Office.
This news release contains forward-looking
statements that involve risks and uncertainties, including technological
advances in the medical field, product demand and market acceptance, actions
of regulatory bodies, the impact of competitive products and pricing,
and other risks detailed in the company's filings with the Securities
and Exchange Commission. These forward-looking statements are based on
estimates and assumptions made by management of the company and are believed
to be reasonable, though are inherently uncertain and difficult to predict.
Actual results or experience could differ materially from the forward-looking
statements.
FOR ADDITIONAL
INFORMATION:
 |
- Media Contacts:
- Deborah
Spak, (847) 948-2349
Margaret Shubny,
(847) 948-3951
- Investor Contacts:
- Neville Jeharajah,
(847) 948-2875
Mary Kay Ladone,
(847) 948-3371
|
| |
|