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CERUS AND BAXTER
SUBMIT CE MARK APPLICATION FOR EUROPEAN APPROVAL OF THE INTERCEPT PLATELET
SYSTEM
Concord, Calif. and
Deerfield, Ill., January 2, 2001 - Cerus Corporation (Nasdaq: CERS) and
Baxter Healthcare Corporation today announced that they have submitted
a CE Mark application for approval to market the Intercept Platelet System
in Europe. The system, which is being jointly developed by Cerus and Baxter
Healthcare Corporation, is designed to inactivate viruses, bacteria, other
pathogens and white blood cells in platelets intended for transfusion.
If approved, the Intercept Platelet System will be the only system commercially
available to enhance the safety of platelet transfusions through pathogen
inactivation.
"This is a landmark achievement
which was accomplished through a concerted effort between both Baxter
and Cerus," said Stephen T. Isaacs, president and chief executive officer
of Cerus. "We look forward to the approval of the Intercept Platelet System
and working with Baxter to launch the first system to inactivate pathogens
in platelets."
Harry M. Jansen Kraemer, Jr.,
chairman and chief executive officer of Baxter said, "We are very pleased
with the significant progress of the Cerus and Baxter teams. This is a
very important step toward enhancing the safety of platelet transfusions
in Europe."
Approximately 1.3 million platelet
transfusions are performed annually in Europe to prevent bleeding in a
variety of patients, including those undergoing cancer therapy and surgical
procedures. While donated platelets are generally tested for a limited
number of specific pathogens, testing does not eliminate the risk of viral
contamination, and most tests are not designed to screen for bacteria.
Bacterial contamination is of particular concern as bacteria quickly grow
in nutrient-rich platelet concentrates, which are stored at room temperature.
Also, white blood cells from donated platelets can potentially result
in graft-vs-host disease and other severe immune reactions in the transfusion
recipient. The Intercept Platelet System is designed to inactivate viruses,
bacteria, other pathogens and white blood cells in donated platelets prior
to transfusion.
ABOUT CERUS
Cerus Corporation is developing medical systems and therapeutics based
on the company's proprietary Helinx technology for inactivating disease-causing
agents. Helinx is designed to target and lock DNA or RNA, and has the
ability to prevent the replication of viruses, bacteria and other pathogens
and to control cellular proliferation. The company's most advanced programs
are focused on systems to enhance the safety of the world's blood supply.
These Intercept Blood Systems, based on the Helinx technology, are designed
to inactivate viruses, bacteria and other pathogens. The Concord, California-based
biopharmaceutical company, in collaboration with its development and commercialization
partner Baxter Healthcare Corporation, has submitted a CE Mark Application
for marketing approval of the Intercept Platelet System in Europe. In
addition, the company is conducting clinical trials of the Intercept Blood
Systems in the United States: a Phase III trial for platelets, a Phase
III trial for plasma and a Phase Ic trial for red blood cells.
ABOUT BAXTER
Baxter Healthcare Corporation is the principal domestic operating subsidiary
of Baxter International (NYSE: BAX). Baxter International, through its
subsidiaries, is a global medical products and services company that provides
critical therapies for people with life-threatening conditions. The company's
products and services in bioscience (biopharmaceuticals and blood collection,
separation and storage devices), medication delivery and renal therapy
are used by health-care providers and their patients more than 100 countries.
Helinx is a trademark of
Cerus Corporation
Intercept Blood System, Intercept Platelet System, Intercept Plasma
System and Intercept Red Blood Cell System are trademarks of
Baxter International, Inc.
Statements in this news release
regarding product development, clinical development, regulatory activity
and product potential are forward-looking statements that involve risks
and uncertainties. Actual results could differ materially from the above
forward-looking statements as a result of certain factors, including the
uncertainty of the timing and results of any clinical trials, action by
regulatory authorities, the uncertainty of market acceptance of any products,
competitive conditions, the uncertainty of future financing and other
factors discussed in the companies' 1999 Annual Report on Form 10-K and
Cerus' Prospectus dated November 1, 2000.
FOR ADDITIONAL
INFORMATION:
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Media
Contacts:
Sylvia
Wheeler, Cerus
Director, Corporate Communications Corporation
(925) 288-6061
Margaret Stanford Shubny,
Baxter
Director, Corporate Communications
(847) 948-3951
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